PTPRM antibody
Principal name
PTPRM antibody
Alternative names for PTPRM antibody
PTPRL1, R-PTP-mu, RPTPU, Receptor-type tyrosine-protein phosphatase mu, Protein-tyrosine phosphatase mu
Ncbi ID
9606, NP_001098714.1, AAH51651.1, NM_001105244, NP_033010.2, BC058614, NM_008984, NM_002845
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of PTPRM antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be sigling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP possesses an extracellular region; a single transmembrane region; and two tandem catalytic domains; and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain; an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1; which may be necessary for the downstream sigling in response to cell-cell adhesion. Altertive splicing results in multiple transcripts encoding distinct isoforms.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA317226 | PTPRM (Internal Region) antibody |
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| PTPRM Rabbit Polyclonal (Internal) Antibody | |||||||
 |
Rabbit | Aff - Purified | Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt | P |
50 µg /
$425.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA317227 | PTPRM (Internal Region) antibody |
||||||
| PTPRM Rabbit Polyclonal (Internal) Antibody | |||||||
|
Rabbit | Aff - Purified | Bear, Bov, Bt, Eq, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt | P |
50 µg /
$425.00
|
||
| OriGene Technologies, Inc. | |||||||