TMEM38A antibody

Principal name

TMEM38A antibody

Alternative names for TMEM38A antibody

Transmembrane protein 38A, TRICA, TRIC-A, Trimeric intracellular cation channel type A

SwissProt ID

A4FV75 (Bovin), A5A6S6 (Rabit), A6ZIQ8 (Rat), Q3TMP8 (Mouse), Q5ZK43 (Chick), Q9H6F2 (Human)

Gene ID

79041 (TMEM38A), 306327 (Tmem38a), 74166

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TMEM38A antibody

Intracellular Ca2+ levels are important in proper cellular functions and have prominent roles in various cell sigling pathways and are crucial for muscle contractions. Indeed, an important step leading to muscle contraction is the massive release of Ca2+ ions from the endoplasmic /sarcoplasmic reticulum (ER/SR) to the cytosol. A battery of results suggest that specific K+ channels are important to counteract the Ca2+ outflow in order to neutralize the negative potential created by the movement of Ca2+ ions. It is believed that TRIC channels are responsible for neutralizing this negative potential. Trimeric intracellular cation-specific (TRIC) channels are critical for proper magement of intracellular stores. TRIC-A and TRIC-B both belong to this family and are both permeable to monovalent ions with a preference for K+ . Both channels are localized to the ER/SR membrane. Each TRIC subunit contains three transmembrane domains, a cytoplasmic C-terminus and a lumil N-terminus. Functiol entities are formed by homotrimerizarion. The activity of TRIC-A is regulated by voltage whereas that of TRIC-B can be regulated by different mechanisms. Knock out studies of these channels have shown that TRIC-A knock mice are viable while those of TRIC-B die at the neotal stage. TRIC-A is mostly expressed in excitable tissues like the brain and muscle while TRIC-B is ubiquitously expressed.

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMEM38A antibody

  Rabbit Polyclonal TMEM38A Antibody  
Western blot analysis of TMEM38A in rat skeletal muscle tissue lysate with TMEM38A antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / $325.00
  OriGene Technologies, Inc.

TMEM38A antibody

  Rabbit polyclonal Anti-TRIC-B  
Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and SH-SY5Y (lanes 3 and 6) lysates: 1-3. Anti-TRIC-B antibody, (1:200).4-6. Anti-TRIC-B antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / $435.00
  OriGene Technologies, Inc.

TMEM38A antibody

  Rabbit polyclonal Anti-TRIC-A  
Western blot analysis of rat brain lysate (lanes 1 and 4) and mouse brain membrane (lanes 2 and 5) and skeletal muscle (lanes 3 and 6): 1-3. Anti-TRIC-A antibody, (1:200). 4-6. Anti-TRIC-A antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / $435.00
  OriGene Technologies, Inc.

TMEM38A antibody

  Rabbit Polyclonal Anti-TMEM38A Antibody  
WB Suggested Anti-TMEM38A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye WB
50 µg / $325.00
  OriGene Technologies, Inc.

TMEM38A (C-term) antibody

Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / $430.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TMEM38A - human gene knockout kit via CRISPR

TMEM38A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / $1,200.00
  OriGene Technologies, Inc.

TMEM38A - human gene knockout kit via CRISPR

TMEM38A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / $1,290.00
  OriGene Technologies, Inc.

TMEM38A - human gene knockout kit via CRISPR

TMEM38A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / $1,290.00
  OriGene Technologies, Inc.

TMEM38A - human gene knockout kit via CRISPR

TMEM38A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / $1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TMEM38A

  Recombinant protein of human transmembrane protein 38A (TMEM38A)  
TMEM38A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / $680.00

Special Price: 20 µg / $398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

TMEM38A overexpression lysate

TMEM38A overexpression lysate  
0.1 mg / $280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TMEM38A (mGFP-tagged) - Human transmembrane protein 38A (TMEM38A), 200 uL, >10^7 TU/mL

Lenti ORF particles, TMEM38A (mGFP-tagged) - Human transmembrane protein 38A (TMEM38A), 200 uL, >10^7 TU/mL  
200 µl / $960.00
  OriGene Technologies, Inc.

Lenti ORF particles, TMEM38A (Myc-DDK tagged) - Human transmembrane protein 38A (TMEM38A) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TMEM38A (Myc-DDK tagged) - Human transmembrane protein 38A (TMEM38A) , 200 uL, >10^7 TU/mL  
200 µl / $860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tmem38a (GFP-tagged) - Mouse transmembrane protein 38A (Tmem38a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem38a (GFP-tagged) - Mouse transmembrane protein 38A (Tmem38a), 200 uL, >10^7 TU/mL  
200 µl / $880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tmem38a (Myc-DDK-tagged) - Mouse transmembrane protein 38A (Tmem38a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem38a (Myc-DDK-tagged) - Mouse transmembrane protein 38A (Tmem38a), 200 uL, >10^7 TU/mL  
200 µl / $780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tmem38a (GFP-tagged ORF) - Rat transmembrane protein 38a (Tmem38a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem38a (GFP-tagged ORF) - Rat transmembrane protein 38a (Tmem38a), 200 uL, >10^7 TU/mL  
200 µl / $880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tmem38a (Myc-DDK-tagged ORF) - Rat transmembrane protein 38a (Tmem38a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem38a (Myc-DDK-tagged ORF) - Rat transmembrane protein 38a (Tmem38a), 200 uL, >10^7 TU/mL  
200 µl / $780.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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