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PSMC2 / MSS1 antibody

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Principal name

PSMC2 / MSS1 antibody

Alternative names for PSMC2 / MSS1 antibody

26S protease regulatory subunit 7, Proteasome 19S S7, 26S proteasome AAA-ATPase subunit RPT1, Proteasome 26S subunit ATPase 2

SwissProt ID

O42931 (Schpo), P33299 (Yeast), P35998 (Human), P46471 (Mouse), P46472 (Xenla), Q18787 (Caeel), Q5E9F9 (Bovin), Q63347 (Rat), Q9SSB5 (Arath)

Gene ID

5701 (PSMC2), 25581 (Psmc2)

Ncbi ID

9606, NP_002794, NP_001191382.1, NM_033236, NM_002803

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Dros (Drosophila), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PSMC2 / MSS1 antibody

The 26S protease is involved in the ATP-dependent degradation of ubiquitited proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, PSMC2 is a positive modulator of Tat-mediated transactivation.The 26S proteasome is a multicatalytic proteise complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Bouwmeester,T., et al., (2004) Nat. Cell Biol. 6 (2), 97-105

H00005701-M01 - PSMC2 / MSS1
Immunofluorescence of monoclonal antibody to PSMC2 on HeLa cell. [antibody concentration 10 ug/ml]
H00005701-M01 - PSMC2 / MSS1
PSMC2 monoclonal antibody (M01), clone 4C10-2C8 Western Blot analysis of PSMC2 expression in SW-13 ( Cat # L005V1 ).
ARP38189_T100 - PSMC2 / MSS1
Human Jurkat; WB Suggested Anti-PSMC2 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate; PSMC2 antibody - N-terminal region (ARP38189_T100) in Human Jurkat cells using Western Blot
ARP34239_P050 - PSMC2 / MSS1
Human OVCAR-3; WB Suggested Anti-PSMC2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: OVCAR-3 cell lysate; PSMC2 antibody - N-terminal region (ARP34239_P050) in Human OVCAR-3 cells using Western Blot
TA332487 - PSMC2 / MSS1
Western blot analysis of extracts of various cell lines, using PSMC2 antibody.
TA332487 - PSMC2 / MSS1
Immunohistochemistry of paraffin-embedded human endometrial cancer using PSMC2 antibody at dilution of 1:200 (400x lens).
TA332487 - PSMC2 / MSS1
Immunohistochemistry of paraffin-embedded human thyroid cancer using PSMC2 antibody at dilution of 1:200 (400x lens).
TA332487 - PSMC2 / MSS1
Immunofluorescence analysis of U2OS cell using PSMC2 antibody. Blue: DAPI for nuclear staining.
TA335804 - PSMC2 / MSS1
WB Suggested Anti-PSMC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: OVCAR-3 cell lysate
TA335805 - PSMC2 / MSS1
WB Suggested Anti-PSMC2 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate
TA350186 - PSMC2
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: 231 cells, Primary antibody: (PSMC2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
TA350186 - PSMC2
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (PSMC2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
TA350186 - PSMC2
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (PSMC2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
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  2. Highly Validated (1)

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMC2 / MSS1 antibody
  Rabbit anti-PSMC2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using PSMC2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / $335.00
  OriGene Technologies, Inc.
+3 additional images

Highly validated antibody!

PSMC2 / MSS1 antibody
  Rabbit Polyclonal Anti-PSMC2 Antibody  
WB Suggested Anti-PSMC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: OVCAR-3 cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Por, Rb, Rt WB
50 µg / $360.00
  OriGene Technologies, Inc.

PSMC2 / MSS1 antibody
  Rabbit Polyclonal Anti-PSMC2 Antibody  
WB Suggested Anti-PSMC2 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, GP, Hu, Ms, Por, Rb, Rt WB
0.1 mg / $360.00
  OriGene Technologies, Inc.

PSMC2 / MSS1 antibody
  Rabbit Polyclonal Anti-PSMC2 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: 231 cells, Primary antibody: (PSMC2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / $335.00
  OriGene Technologies, Inc.
+2 additional images

CRISPR

Catalog No. Species Donor Vector  

PSMC2 - human gene knockout kit via CRISPR
PSMC2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / $1,290.00
  OriGene Technologies, Inc.

PSMC2 - human gene knockout kit via CRISPR
PSMC2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / $1,290.00
  OriGene Technologies, Inc.

PSMC2 - human gene knockout kit via CRISPR
PSMC2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / $1,290.00
  OriGene Technologies, Inc.

PSMC2 - human gene knockout kit via CRISPR
PSMC2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / $1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PSMC2 (mGFP-tagged) - Human proteasome (prosome, macropain) 26S subunit, ATPase, 2 (PSMC2), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, PSMC2 (mGFP-tagged) - Human proteasome (prosome, macropain) 26S subunit, ATPase, 2 (PSMC2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / $1,082.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, PSMC2 (Myc-DDK tagged) - Human proteasome (prosome, macropain) 26S subunit, ATPase, 2 (PSMC2), transcript variant 1 , 200 uL, >10^7 TU/mL
Lenti ORF particles, PSMC2 (Myc-DDK tagged) - Human proteasome (prosome, macropain) 26S subunit, ATPase, 2 (PSMC2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / $969.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Psmc2 (GFP-tagged ORF) - Rat proteasome (prosome, macropain) 26S subunit, ATPase 2 (Psmc2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Psmc2 (GFP-tagged ORF) - Rat proteasome (prosome, macropain) 26S subunit, ATPase 2 (Psmc2), 200 uL, >10^7 TU/mL  
200 µl / $1,061.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Psmc2 (Myc-DDK-tagged ORF) - Rat proteasome (prosome, macropain) 26S subunit, ATPase 2 (Psmc2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Psmc2 (Myc-DDK-tagged ORF) - Rat proteasome (prosome, macropain) 26S subunit, ATPase 2 (Psmc2), 200 uL, >10^7 TU/mL  
200 µl / $949.00
  OriGene Technologies, Inc.
 

12 Item(s)

per page
12 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. CRISPR (4)
  2. Human Lenti ORF Particle (2)
  3. Primary Antibody (4)
  4. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (4)
Target
  1. PSMC2 / MSS1 (4)
Reactivity
  1. Human (Hu) (4)
  2. Rat (Rt) (4)
  3. Mouse (Ms) (3)
  4. Canine (Can) (2)
  5. Guinea Pig (GP) (2)
  6. Porcine (Por) (2)
  7. Rabbit (Rb) (2)
  8. Bovine (Bov) (1)
Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Enzyme Immunoassay (E) (1)
  3. Paraffin Sections (P) (1)
Presentation
  1. Purified (4)
Host
  1. Rabbit (4)
Images
  1. 1 image (4)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (4)
  2. IHC (2)
  3. Immunofluorescence (IF) (1)
Species (CRISPR)
  1. Human (4)
Donor Vector
  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
  3. RFP-BSD (1)
  4. mBFP-Neo (1)
Manufacturer
  1. Acris - OriGene (12)
Service
 
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