DYRK1A antibody

Principal name

DYRK1A antibody

Alternative names for DYRK1A antibody

DYRK, MNB, MNBH, Protein kinase minibrain homolog, HP86, Dual specificity YAK1-related kinase, Dual specificity tyrosine-phosphorylation-regulated kinase 1A

SwissProt ID

P85051 (Rabit), Q13627 (Human), Q2TAE3 (Xenla), Q61214 (Mouse), Q63470 (Rat)

Gene ID

1859 (DYRK1A), 13548 (Dyrk1a), 25255

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit), Bov (Bovine), Can (Canine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Sheep, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C)

Background of DYRK1A antibody

This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kise (DYRK) family. This member contains a nuclear targeting sigl sequence, a protein kise domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a sigling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Altertive splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008].

General readings

1. Baek KH  et al. Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature 459:1126-30 (2009). WB ; Human .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DYRK1A antibody

  Goat Anti-DYRK1A Antibody  
(0.5ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / $325.00
  OriGene Technologies, Inc.

DYRK1A antibody

  Rabbit polyclonal anti-DYR1A antibody  
Western blot analysis of extracts from HepG2 cells, using DYR1A antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / $325.00
  OriGene Technologies, Inc.

DYRK1A (C-term) antibody

  Rabbit Polyclonal DYRK1A Antibody  
Western blot analysis of DYRK1A in HeLa cell lysate with DYRK1A antibody at (A) 1 and (B) 2 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / $325.00
  OriGene Technologies, Inc.

DYRK1A antibody

  Rabbit Polyclonal Anti-Dyrk1a Antibody  
WB Suggested Anti-Dyrk1a Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Mouse Heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / $325.00
  OriGene Technologies, Inc.

DYRK1A antibody

  Rabbit Polyclonal Anti-DYRK1A Antibody  
WB Suggested Anti-DYRK1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / $325.00
  OriGene Technologies, Inc.

DYRK1A antibody

Western blot analysis of Dyrk1A antibody (Cat.-No.: AP06728PU-N) in extracts from HepG2 cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / $330.00
  Acris Antibodies GmbH

DYRK1A (N-term) antibody

Western blot analysis of DYRK1A Antibody (N-term) in 293 cell line lysates (35ug/lane). DYRK1A (arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu WB
0.4 ml / $330.00
  Acris Antibodies GmbH

DYRK1A (Center) antibody

Western blot analysis of DYRK1A Antibody (Center) polyclonal antibody in HL60 cell line lysates (35ug/lane). DYRK1A (arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu WB
0.4 ml / $330.00
  Acris Antibodies GmbH

DYRK1A antibody

Western blot analysis using DyrK1A antibody Rabbit Serum Rt C, E, WB
0.2 ml / $460.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

DYRK1A - human gene knockout kit via CRISPR

DYRK1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / $1,200.00
  OriGene Technologies, Inc.

DYRK1A - human gene knockout kit via CRISPR

DYRK1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / $1,290.00
  OriGene Technologies, Inc.

DYRK1A - human gene knockout kit via CRISPR

DYRK1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / $1,290.00
  OriGene Technologies, Inc.

DYRK1A - human gene knockout kit via CRISPR

DYRK1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / $1,290.00
  OriGene Technologies, Inc.

Dyrk1a - mouse gene knockout kit via CRISPR

Dyrk1a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / $1,200.00
  OriGene Technologies, Inc.

Dyrk1a - mouse gene knockout kit via CRISPR

Dyrk1a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / $1,290.00
  OriGene Technologies, Inc.

Dyrk1a - mouse gene knockout kit via CRISPR

Dyrk1a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / $1,290.00
  OriGene Technologies, Inc.

Dyrk1a - mouse gene knockout kit via CRISPR

Dyrk1a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / $1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DYRK1A (full length, C-term DDK tag, transcript variant 1)

  Recombinant protein of human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9 cells  
DYRK1A Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / $399.00
  OriGene Technologies, Inc.

DYRK1A (159-479, His-tag)

DYRK1A Human Purified > 80 % by SDS - PAGE E. coli
0.5 mg / $790.00
  Acris Antibodies GmbH

DYRK1A (159-479, His-tag)

DYRK1A Human Purified > 80 % by SDS - PAGE E. coli
0.1 mg / $340.00
  Acris Antibodies GmbH

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