Ataxin-1 antibody

Principal name

Ataxin-1 antibody

Alternative names for Ataxin-1 antibody

Ataxin 1, ATXN1, ATX1, SCA1, Spinocerebellar ataxia type 1 protein

SwissProt ID

P54253 (Human), P54254 (Mouse), Q63540 (Rat)

Gene ID

6310 (ATXN1), 20238 (Atxn1), 25049

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP)

Background of Ataxin-1 antibody

The autosomal domint cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spil cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, desigted spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retil degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene.

  1. Quick-Filters:
  2. Highly Validated (3)

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ataxin-1 antibody

Transfected cell immunoblot: COS cells transiently transfected with Ataxin-1 and Kv2.1 plasmids and probed with N76/8 TC supe. Mouse IgG2b N76/8 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / $320.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

Transfected cell immunoblot: COS cells transiently transfected with Ataxin-1 and Kv2.1 plasmids and probed with N76/8 TC supe. Mouse IgG2b N76/8 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / $380.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues (left) and lung cancer tissues (right) using ATXN1 antibody Cat.-No AM06558SU-N with DAB staining. Mouse IgG1 2F5 Ascites Hu E, F, ICC/IF, P, WB
0.1 ml / $330.00
  Acris Antibodies GmbH

Ataxin-1 antibody

  Rabbit Polyclonal Ataxin 1 Antibody  
Western blot analysis of Ataxin 1 expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / $325.00
  OriGene Technologies, Inc.

Ataxin-1 antibody

  Rabbit Polyclonal Ataxin 1 (Ser776) Antibody (Phospho-specific)  
Western blot analysis of Ataxin 1 phosphorylation expression in Adriamycin treated HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / $325.00
  OriGene Technologies, Inc.

Ataxin-1 antibody

  Rabbit anti-ATXN1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using ATXN1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / $325.00
  OriGene Technologies, Inc.

Ataxin-1 antibody

  Rabbit Polyclonal Anti-ATXN1 Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: 293T cells, human fetal brain tissue, Primary antibody: (ATXN1 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / $325.00
  OriGene Technologies, Inc.

Ataxin-1 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N65/37 Supernatant Hu, Ms, Rt ICC/IF, WB
5 ml / $320.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

adult mouse brain immunoblot: extracts of cerebella from Ataxin-1 KO and WT mice and probed with N76/3 TC supe. Image courtesy of Drs. Paymaan Jafad-Nejad and Huda Zoghbi, Baylor College of Medicine. Mouse IgG1 N76/3 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / $320.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 N65/37 Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / $380.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

adult mouse brain immunoblot: extracts of cerebella from Ataxin-1 KO and WT mice and probed with N76/3 TC supe. Image courtesy of Drs. Paymaan Jafad-Nejad and Huda Zoghbi, Baylor College of Medicine. Mouse IgG1 N76/3 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / $380.00
  Antibodies Incorporated

NeuroMab

Ataxin-1 antibody

Western blot analysis of anti-ATXN1 Antibody (S776) (Cat.#AP12458PU-N) in CEM cell line lysates (35ug/lane). ATXN1 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / $330.00
  Acris Antibodies GmbH

Ataxin-1 (C-term) antibody

Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms E, ICC/IF, P
50 µl / $430.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Atxn1 - mouse gene knockout kit via CRISPR

Atxn1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / $1,200.00
  OriGene Technologies, Inc.

Atxn1 - mouse gene knockout kit via CRISPR

Atxn1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / $1,290.00
  OriGene Technologies, Inc.

Atxn1 - mouse gene knockout kit via CRISPR

Atxn1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / $1,290.00
  OriGene Technologies, Inc.

Atxn1 - mouse gene knockout kit via CRISPR

Atxn1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / $1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Ataxin-1 (transcript variant 1)

  Recombinant protein of human ataxin 1 (ATXN1), transcript variant 1  
Ataxin-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $680.00
  OriGene Technologies, Inc.

Ataxin-1 (transcript variant 2)

  Recombinant protein of human ataxin 1 (ATXN1), transcript variant 2  
Ataxin-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ATXN1 (mGFP-tagged) - Human ataxin 1 (ATXN1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ATXN1 (mGFP-tagged) - Human ataxin 1 (ATXN1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / $1,050.00
  OriGene Technologies, Inc.

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn