Antibodies to Cyclin Family - Product Review 16
Introduction
Oscillations in the activity of the Cdk family of protein kinases drive the eukaryotic cell cycle. These enzymes consist of a catalytic (Cdk) and a regulatory subunit (Cyclin).
Their activity is regulated by phosphorylation of Cdks, binding of stoichiometric kinase inhibitors and regulated proteolysis of the cyclins.The Cdk/cyclin family contains five Cdks (Cdk1, 2, 3, 4 and 6) and four cyclin classes (cyclin A, B, D and E, see table below.) that regulate the cell cycle; three Cdks (Cdk7, 8 and 9) and three cyclin classes (cyclin C, H and T) that regulate transcription. Activating the cell-cycle Cdks requires phosphorylation of a conserved threonine as well as binding of cyclin.
Antibody Tools for Detection of Cyclin Proteins
OriGene Technologies offers a broad panel of monoclonal and polyclonal antibodies for the immunological detection of members of the Cyclin protein family.
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Available Antibodies to the Cyclin Family
Anti- Cyclin A (CCNA), Cyclin A1 (CCNA1), Cyclin B1 (CCNB), Cyclin B2 (CCNB2), Cyclin B3 (CCNB3), Cyclin C (CCNC), Cyclin D1 (CCND1), Cyclin D2 (CCND2), Cyclin D3 (CCND3), Cyclin E (CCNE), Cyclin E1 (CCNE1), Cyclin E2 (CCNE2), Cyclin G (CCNG), Cyclin G1 (CCNG1), Cyclin G2 (CCNG2), Cyclin H (CCNH), Cyclin I (CCNI), Cyclin J (CCNJ), Cyclin K (CCNK), Cyclin L1 (CCNL1), Cyclin L2 (CCNL2), Cyclin T1 (CCNT1), Cyclin T2 (CCNT2) antibody
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- Cited (2)
Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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AP09514PU-N | Cyclin B1 antibody |
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Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
0.1 mg /
$300.00
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OriGene Technologies GmbH | |||||||
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Published recently! |
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AP09514PU-S | Cyclin B1 antibody |
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Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
50 µg /
$230.00
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OriGene Technologies GmbH | |||||||
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Published recently! |
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AP01169PU-N | Cyclin B1 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | WB |
0.1 mg /
$370.00
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OriGene Technologies GmbH | |||||||
AP06381PU-N | Cyclin B1 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
$370.00
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OriGene Technologies GmbH | |||||||
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AP09487PU-N | Cyclin B1 pSer147 antibody |
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Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
0.1 mg /
$300.00
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OriGene Technologies GmbH | |||||||
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AP09487PU-S | Cyclin B1 pSer147 antibody |
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Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
50 µg /
$230.00
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OriGene Technologies GmbH | |||||||
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AP14263PU-N | Cyclin B1 antibody |
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Rabbit | Ig | Aff - Purified | Hu, Ms | WB |
0.4 ml /
$415.00
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OriGene Technologies GmbH |