discontinued

EA101045 Androstenedione ELISA Kit

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EA101045

Properties for Androstenedione ELISA Kit

Product Category ELISA Kits
Quantity 1 kit
Synonyms Androstenedione
Reactivity Hu
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Add. information
Interference:
No significant interference observed with available related molecules.
Application
Specificity:
Natural and recombinant human Androstenedione
Assay Type:
Solid Phase Sandwich ELISA
Signal:
Colorimetric
Sample Type:
Cell culture supernatant, serum, plasma
Sample Volume:
20 ul
Curve Range:
0.019 – 10 ng/mL
Background The steroid hormone Androstenedione is one of the main androgens, besides Testosterone and Dehydroepiandrosterone. Testosterone, the most important biological active androgen, is derived from peripheral enzymatic conversion of Androstenedione. In males, androgens are secreted primarily by the Leydig cells of the testes, to some degree also in the adrenal cortex. In females, the androgens are secreted mainly in the adrenal glands and in the ovary. Around 10% of the androgens are derived from peripheral conversion, mainly of DHEA. Androstenedione and Testosterone show high diurnal variability. The highest levels are measured in the morning. At the age of puberty serum androstenedione levels rise, after menopause they decline again. High androstenedione levels are measured during pregnancy. In women, high levels of androstenedione (47-100% above normal) are generally found in hirsutism, mostly in combination with other androgens as testosterone and DHEA-S. Androstenedione overproduction is due to ovarian dysfunction or may be of adrenal origin. High circulating androstenedione levels are found in women with polycystic ovaries and 21-hydroxylase effect. Significant lower androstenedione levels are found in postmenopausal osteoporosis.
Assaytime 3 hours
Range 0.021 ng/ml
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