AM26025HR-N Human IgG (Fc heavy chain specific) antibody

Search for all "Human IgG"

0.1 mg / $270.00
Delivery Time: 10 working days*
(*) valid for US customers only

Product Description for Human IgG

Properties: (Fc heavy chain specific)
Presentation: HRP
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Human IgG

Product Category Secondary Antibodies
Quantity 0.1 mg
Synonyms Human Immunoglobulin G
Presentation HRP
Reactivity Hu
Applications E, WB
Clonality Monoclonal
Clone EM-07
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Fusion protein of Human IgG Fc fragment
Application ELISA: 0.1-0.5 µg/ml. 
Western blot.
Background Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75% of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.
Concentration 1.0 mg/ml
General Readings
  1. Franklin EC. Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95. PubMed PMID: 47690.
  2. Fuller JM, Keyser JW. Serum immunoglobulins after surgical operation. Clin Chem. 1975 May;21(6):667-71. PubMed PMID: 1122610.
  3. Balogh Z, Merétey K, Falus A, Bozsóky S. Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rheum Dis. 1980 Apr;39(2):129-34. PubMed PMID: 6966908. (Free PMC Article available)
  4. Brinkmann V, Heusser CH. T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors. Cell Immunol. 1993 Dec;152(2):323-32. PubMed PMID: 8258141.
Storage

Store undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Format
Label:
Conjugated with Horseradish Peroxidase of high specific activity and RZ=3
HRP
Buffer System:
PBS
Preservatives:
0.01% (w/v) Thimerosal
Stabilizers:
1% (w/v) high-grade BSA (Protease free)
State:
Liquid purified IgG fraction
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody reacts with Fc part of Human IgG heavy chain and with isolated Fc fragments.
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