AP01217PU-N MCHR2 / GPR145 antibody

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0.1 mg / $330.00
Delivery Time: 10 working days*
(*) valid for US customers only

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Rabbit anti Human MCHR2 / GPR145

Product Description for MCHR2 / GPR145

Rabbit anti Human MCHR2 / GPR145.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for MCHR2 / GPR145

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms G-protein coupled receptor 145, GPRv17, MCH receptor 2, MCH-2R, MCH-R2, MCHR-2, Melanin-concentrating hormone receptor 2, SLT
Presentation Aff - Purified
Reactivity Hu
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 38 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q969V1
Immunogen:
Synthetic peptide, corresponding to amino acids 300-348 of Human MCH-2R.
GeneID:
84539
Application Western Blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Background Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide,which is mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor that migrates between 45-50 kDa on SDS-PAGE. MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen.
Buffer System:
Phosphate buffered saline (PBS), pH~7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of MCH-2R protein.(region surrounding Met332)
Gene ID 84539
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