TA319221 Interleukin-33 (IL33) antibody

Rabbit polyclonal IL-33 antibody Peroxidase Conjugated

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Search for all "Interleukin-33 (IL33)"

0.1 mg / $515.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

Quick Overview

Rabbit anti Human Interleukin-33 (IL33)

Product Description for Interleukin-33 (IL33)

Rabbit anti Human Interleukin-33 (IL33).
Presentation: HRP
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Interleukin-33 (IL33)

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms C9orf26, IL-1F11, IL-33, IL1F11, Interleukin-1 family member 11, NF-HEV, NFHEV, Nuclear factor from high endothelial venules
Presentation HRP
Reactivity Hu
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
O95760
Immunogen:
Full length recombinant human IL-33 protein
GeneID:
90865
Application ELISA: 1/10000 - 1/50000.
WB: 1/1000 - 1/5000.
Background IL-33 (also known as Interleukin-33, Interleukin-1 family member 11, IL-1F11, nuclear factor from high endothelial venules and NF-HEV) is a cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL-33 induces T helper type 2-associated cytokines. IL-33 is a secreted cytokine that is expressed at high levels in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes and is almost undetectable in placenta. The 31 kDa precursor is proteolytically converted to an 18 kDa mature form by CASP1.
Concentration 1.0 mg/ml (by UV absorbance at 280 nm)
General Readings
  1. Hayakawa M, Hayakawa H, Matsuyama Y, Tamemoto H, Okazaki H, Tominaga S. Mature interleukin-33 is produced by calpain-mediated cleavage in vivo. Biochem Biophys Res Commun. 2009 Sep 11;387(1):218-22. doi: 10.1016/j.bbrc.2009.07.018. Epub 2009 Jul 9. PubMed PMID: 19596270.
  2. Lüthi AU, Cullen SP, McNeela EA, Duriez PJ, Afonina IS, Sheridan C, et al. Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity. 2009 Jul 17;31(1):84-98. doi: 10.1016/j.immuni.2009.05.007. Epub 2009 Jun 25. PubMed PMID: 19559631.
  3. Wood IS, Wang B, Trayhurn P. IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes. Biochem Biophys Res Commun. 2009 Jun 19;384(1):105-9. doi: 10.1016/j.bbrc.2009.04.081. Epub 2009 Apr 23. PubMed PMID: 19393621.
  4. Pushparaj PN, Tay HK, H'ng SC, Pitman N, Xu D, McKenzie A, et al. The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9773-8. doi: 10.1073/pnas.0901206106. Epub 2009 Jun 8. PubMed PMID: 19506243. (Free PMC Article available)
Storage Prior to reconstitution store at 2-8°C.
Following reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
Peroxidase (Horseradish)
HRP
Buffer System:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing as stabilizer 10 mg/ml BSA and 0.01% (w/v) Gentamicin Sulfate as preservative
(Do NOT add Sodium Azide!)
State:
Lyophilized
Reconstitution:
Restore with 0.1 mL of deionized water (or equivalent).
Specificity
Specificity:
This antibody reacts to Interleukin-33.
Species:
Human.

Accessory Products

Proteins and/or Positive Controls

Proteins for Interleukin-33 (IL33) (9 products)

Catalog No. Species Pres. Purity   Source  

Interleukin-33 (IL33)

Interleukin-33 (IL33) Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / $299.00
  OriGene Technologies, Inc.

Interleukin-33 (IL33) (transcript variant 1)

Interleukin-33 (IL33) Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / $230.00
  OriGene Technologies, Inc.

Interleukin-33 (IL33) (transcript variant 1)

Interleukin-33 (IL33) Human > 98 %
Preparation: .
Purity Detail: >98%, as determined by Coomassie stained SDS-PAGE.
E. coli
10 µg / $265.00
  OriGene Technologies, Inc.

Interleukin-33 (IL33) (full length, N-term HIS tag, transcript variant 1)

Interleukin-33 (IL33) Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / $205.00
  OriGene Technologies, Inc.

Interleukin-33 (IL33)

Interleukin-33 (IL33) Human >98% by SDS PAGE/HPLC analysis
  OriGene Technologies GmbH

Interleukin-33 (IL33)

Interleukin-33 (IL33) Human Purified > 98 % pure by SDS-PAGE gel and HPLC analyses. E. coli
  OriGene Technologies GmbH

Interleukin-33 (IL33)

Interleukin-33 (IL33) Human Purified > 98 % pure by SDS-PAGE gel and HPLC analyses. E. coli
  OriGene Technologies GmbH

Interleukin-33 (IL33) (112-270)

Interleukin-33 (IL33) Human Purified > 95 % >/= 95% by SDS PAGE E. coli
  OriGene Technologies GmbH

Interleukin-33 (IL33) (112-270)

Interleukin-33 (IL33) Human Purified > 95 % >/= 95% by SDS PAGE E. coli
  OriGene Technologies GmbH

Positive controls for Interleukin-33 (IL33) (1 products)

Catalog No. Species Pres. Purity   Source  

IL33 overexpression lysate

IL33 overexpression lysate
0.1 mg / $295.00
  OriGene Technologies, Inc.
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