AP06144PU-N GLUT1 / SLC2A1 antibody

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0.1 mg / $370.00
Delivery Time: 10 working days*
(*) valid for US customers only

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Rabbit anti Human, Mouse, Rat GLUT1 / SLC2A1

AP06144PU-N

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  • AP06144PU-N

Product Description for GLUT1 / SLC2A1

Rabbit anti Human, Mouse, Rat GLUT1 / SLC2A1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot, Paraffin Sections.

Properties for GLUT1 / SLC2A1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms GLUT-1, Glucose Transporter 1, Glucose transporter type 1, Glucose transporter type 1 erythrocyte/brain, HepG2 glucose transporter, Solute carrier family 2 facilitated glucose transporter member 1
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~55 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P11166
Immunogen:
Synthetic peptide, corresponding to amino acids 441-490 of Human Glut 1.
GeneID:
6513
Application Western blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Background Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter, Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane, and shows a much less dramatic translocation in response to insulin. Glut1 and Glut4 are twelve pass transmembrane proteins (12TM) whose carboxytermini may dictate their cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen.
Buffer System:
Phosphate Buffered Saline (PBS), pH~7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (>95% pure by SDS-PAGE).
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of GLUT1 protein.
Gene ID 6513
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Accessory Products

Proteins and/or Positive Controls

Proteins for GLUT1 / SLC2A1 (1 products)

Catalog No. Species Pres. Purity   Source  

GLUT1 / SLC2A1

GLUT1 / SLC2A1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.
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