DM3547P Galectin-7 antibody

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0.1 mg / $480.00
Delivery Time: 10 working days*
(*) valid for US customers only

Quick Overview

Rat anti Mouse Galectin-7 8J52

DM3547P

Product Description for Galectin-7

Rat anti Mouse Galectin-7 8J52.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Galectin-7

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Gal-7, HKL-14, LGALS7, LGALS7B, PI7, PIG1, p53-induced gene 1 protein
Presentation Purified
Reactivity Ms
Applications WB
Clonality Monoclonal
Clone 8J52
Host Rat
Isotype IgG2
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O54974
Immunogen:
Purified Recombinant Mouse Galectin-7
Remarks:
Mouse myeloma fused with spleen cells from a Rat
Application Western Blot: 1/500-1/1000.
Background Galectins belong to a family of related beta-galactoside-binding lectins, also referred to as S-type or S-Lac lectins. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. Galectin 7 is thought to be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Galectin 7 has been implicated in apoptosis and is believed to upregulate MMP9 and as such be involved in the progression of tumorigenesis.

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.
Storage Prior to reconstitution store at -70°C.
Following reconstitution store the antibody (in aliquots) at -20°C for 6 month.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A/G Affinity Chromatography
Buffer System:
0.2 μm filtered solution in PBS
Stabilizers:
None
State:
Lyophilized purified IgG fraction from Culture Supernatant
Purified
Reconstitution:
Restore with 200 µl sterile PBS and the final concentration is 500 µg/ml.
Specificity
Specificity:
This antibody detects Mouse Galectin-7. 
Other species not tested.

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