AP55854PU-S DPYSL2 / CRMP2 pSer522 antibody

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Search for all "DPYSL2 / CRMP2"

50 µg / $235.00
Delivery Time: 7-10 working days*
(*) valid for US customers only

Quick Overview

Rabbit anti Human, Mouse, Rat DPYSL2 / CRMP2

Product Description for DPYSL2 / CRMP2

Rabbit anti Human, Mouse, Rat DPYSL2 / CRMP2.
Properties: pSer522
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for DPYSL2 / CRMP2

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms Collapsin response mediator protein 2, DRP-2, Dihydropyrimidinase-related protein 2, N2A3
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Molecular weight 62 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q16555
Immunogen:
Peptide sequence around phosphorylation site of Serine 522(K-T-S(p)-P-A) derived from Human CRMP-2 (KLH-conjugated)
GeneID:
1808
Property pSer522
Application Western blot: 1:500~1:1000.
Background CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Concentration 1.0 mg/ml
General Readings
  1. Goshima Y, Nakamura F, Strittmatter P, Strittmatter SM. Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33. Nature. 1995 Aug 10;376(6540):509-14. PubMed PMID: 7637782.
  2. Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M, Nonaka M. A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution. Gene. 1996 Nov 21;180(1-2):157-63. PubMed PMID: 8973361.
  3. Kitamura K, Takayama M, Hamajima N, Nakanishi M, Sasaki M, Endo Y, et al. Characterization of the human dihydropyrimidinase-related protein 2 (DRP-2) gene. DNA Res. 1999 Oct 29;6(5):291-7. PubMed PMID: 10574455.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography using epitope-specific peptide
Buffer System:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse, Rat
Specificity
Specificity:
The antibody detects endogenous levels of DPYSL2 only when phosphorylated at serine 522.

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