AP12304PU-N Cyclin D1 (N-term) antibody

See related secondary antibodies

Search for all "Cyclin D1"

0.4 ml / $330.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

Quick Overview

Rabbit anti Human Cyclin D1

Product Description for Cyclin D1

Rabbit anti Human Cyclin D1.
Properties: (N-term)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Cyclin D1

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms BCL-1 oncogene, BCL1, CCND1, Cyclin-D1, G1/S-specific cyclin-D1, PRAD-1 oncogene, PRAD1
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P24385
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CCND1.
GeneID:
595
Property N-term
Application ELISA: 1/1,000.
Western Blot: 1/50-1/100.
Background CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of the gene encoding this protein, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration lot specific
General Readings
  1. He,Y.Y., Cancer Res. 68 (10), 3752-3758 (2008)
  2. Marsit,C.J., Clin. Cancer Res. 14 (8), 2371-2377 (2008)
  3. Caldon,C.E., Cancer Res. 68 (8), 3026-3036 (2008)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Buffer System:
PBS with 0.09% (W/V) Sodium Azide as preservative.
State:
Liquid purified Ig fraction.
Purified
Specificity
Specificity:
This antibody detects CCND1 (N-term).
Species:
Human.
Gene ID 595
FocusOn and Reviews
Reviews:

Accessory Products

Proteins and/or Positive Controls

Proteins for Cyclin D1 (2 products)

Catalog No. Species Pres. Purity   Source  

Cyclin D1

Cyclin D1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $438.00
  OriGene Technologies, Inc.

Cyclin D1 (full length, C-term flag tag)

Cyclin D1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / $399.00
  OriGene Technologies, Inc.
  • LinkedIn