AP51001PU-N Cochlin (Center) antibody

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0.4 ml / $415.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

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Rabbit anti Human Cochlin


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  • AP51001PU-N
  • AP51001PU-N

Product Description for Cochlin

Rabbit anti Human Cochlin.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Flow Cytometry, Western blot / Immunoblot.

Properties for Cochlin

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms COCH, COCH-5B2, COCH5B2
Presentation Aff - Purified
Reactivity Hu
Applications F, P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Molecular weight 59483 Da
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic peptide between 398-428 amino acids from the Central region of human COCH
Property Center
Application ELISA: 1/1000.
Western blot: 1/100 - 1/500.
Immunohistochemistry on paraffin sections: 1/10 - 1/50.
Flow Cytometry: 1/10 - 1/50.
Background The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq].
Concentration lot specific
General Readings
  1. Ikezono, T., et al. Acta Otolaryngol. 130(8):881-887(2010)
  2. Yao, J., et al. J. Biol. Chem. 285(20):14909-14919(2010)
  3. Baek, J.I., et al. Clin. Genet. 77(4):399-403(2010)
  4. Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  5. Lee, E.S., et al. Invest. Ophthalmol. Vis. Sci. 51(4):2060-2066(2010)

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Affinity chromatography on Protein A
Buffer System:
0.09% (W/V) sodium azide
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
This antibody reacts to COCH.
Gene ID 1690

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