AP00026PU-N CFLAR / Casper / I-FLICE (Long Form) antibody

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0.1 mg / $290.00
Delivery Time: 2-3 working days*
(*) valid for US customers only

Quick Overview

Rabbit anti Human, Mouse, Rat CFLAR / Casper / I-FLICE

Product Description for CFLAR / Casper / I-FLICE

Rabbit anti Human, Mouse, Rat CFLAR / Casper / I-FLICE.
Properties: (Long Form)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for CFLAR / Casper / I-FLICE

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O15519
Immunogen:
Synthetic peptide near the C-terminus of human FLIPα/FLIPL form.
GeneID:
8837
Property Long Form
Application Western Blot: 0.5-4 μg/ml.
Background Caspase-8 (FLICE) and -10 (FLICE2) are two pivotal members in the caspase family. Human and viral FLICE-inhibitory proteins were designated as v-FLIPs and c-FLIP, respectively. c-FLIP was cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH AND CLARP. c-FLIP contains two death effector domains and has sequence homology to caspase-8. c-FLIP interacts with adapter protein FADD and caspaser-8 and -10, and potently inhibits apoptosis induced by all known death receptors. Two splice variants of c-FLIP have been identified and termed FLIPL and FLIPs. The mRNA for c-FLIP is predominantly expressed in muscle and lymphoid tissue.
Concentration 0.2 mg/ml
Storage Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity purified
Buffer System:
PBS, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thymerosal
State:
Liquid purified Ig
Aff - Purified
Specificity
Specificity:
The immunoaffinity-purified antibody detects 58 kDa FLIPL on SDS-PAGE immunoblots, in samples from human, mouse and rat origins. The antibody recognizes only the FLIPL form.
Species:
Human, Mouse, Rat.
Gene ID 8837
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Accessory Products

Proteins and/or Positive Controls

Proteins for CFLAR / Casper / I-FLICE (3 products)

Catalog No. Species Pres. Purity   Source  

CFLAR / Casper / I-FLICE (transcript variant 3)

CFLAR / Casper / I-FLICE Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $680.00
  OriGene Technologies, Inc.

CFLAR / Casper / I-FLICE (1-480)

CFLAR / Casper / I-FLICE Human Purified > 85 % E. coli
0.5 mg / $785.00
  OriGene Technologies GmbH

CFLAR / Casper / I-FLICE (1-480)

CFLAR / Casper / I-FLICE Human Purified > 85 % E. coli
0.1 mg / $340.00
  OriGene Technologies GmbH

Positive controls for CFLAR / Casper / I-FLICE (1 products)

Catalog No. Species Pres. Purity   Source  

CFLAR overexpression lysate

CFLAR overexpression lysate
0.1 mg / $295.00
  OriGene Technologies, Inc.
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