AM09055PU-N CFLAR / Casper / I-FLICE (1-376) antibody

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0.1 ml / $350.00
Delivery Time: 10 working days*
(*) valid for US customers only

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Mouse anti Human, Mouse, Rat CFLAR / Casper / I-FLICE AT8B12

AM09055PU-N

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  • AM09055PU-N

Product Description for CFLAR / Casper / I-FLICE

Mouse anti Human, Mouse, Rat CFLAR / Casper / I-FLICE AT8B12.
Properties: (1-376)
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Enzyme Immunoassay, Western blot / Immunoblot.

Properties for CFLAR / Casper / I-FLICE

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
Presentation Purified
Reactivity Hu, Ms, Rt
Applications E, ICC/IF, WB
Clonality Monoclonal
Clone AT8B12
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O15519
Immunogen:
Recombinant human FLIP (aa 1-376) purified from E. coli.
GeneID:
8837
Property 1-376
Isotype control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Application ELISA.
Western Blot: 1/500-1/1000.
Immunofluorescence.
Background FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and Caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (Death Receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (Tumor Necrosis Factor Receptor 1).
Concentration 1.0 mg/ml
General Readings
  1. Yu JW, Shi Y., (2008) Oncogene. 27(48):6216–27.
  2. Du C, et al., (2005) Kidney Int. 67(4):1397–409.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography on Protein G
Buffer System:
PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State:
Liquid purified Ig fraction
Purified
Specificity
Specificity:
The antibody recognizes FLIP.
Species:
Human, Mouse and Rat.
Gene ID 8837
FocusOn and Reviews
FocusOns:

Accessory Products

Proteins and/or Positive Controls

Proteins for CFLAR / Casper / I-FLICE (3 products)

Catalog No. Species Pres. Purity   Source  

CFLAR / Casper / I-FLICE (transcript variant 3)

CFLAR / Casper / I-FLICE Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $680.00
  OriGene Technologies, Inc.

CFLAR / Casper / I-FLICE (1-480)

CFLAR / Casper / I-FLICE Human Purified > 85 % E. coli
0.5 mg / $785.00
  OriGene Technologies GmbH

CFLAR / Casper / I-FLICE (1-480)

CFLAR / Casper / I-FLICE Human Purified > 85 % E. coli
0.1 mg / $340.00
  OriGene Technologies GmbH

Positive controls for CFLAR / Casper / I-FLICE (1 products)

Catalog No. Species Pres. Purity   Source  

CFLAR overexpression lysate

CFLAR overexpression lysate
0.1 mg / $295.00
  OriGene Technologies, Inc.
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