Product Description for CD283 / TLR3
Mouse anti Human CD283 / TLR3 1213F10 / TLR3.3.
Properties: (LRR7-LRR8)
Presentation: Alexa Fluor 488
Product is tested for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.
Properties: (LRR7-LRR8)
Presentation: Alexa Fluor 488
Product is tested for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.
Properties for CD283 / TLR3
Product Category | Primary Antibodies |
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Target Category | |
Quantity | 0.1 mg |
Synonyms | Toll-like receptor 3 |
Presentation | Alexa Fluor 488 |
Reactivity | Hu |
Applications | F, ICC/IF, IP, WB |
Clonality | Monoclonal |
Clone | 1213F10 / TLR3.3 |
Host | Mouse |
Isotype | IgG1 |
Molecular weight | 135KDa, 130KDa, 60KDa |
Shipping to | Germany, USA/Canada |
PDF datasheet | View Datasheet |
Manufacturer | Dendritics SAS |
Datasheet Extract
Immunogen |
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Property | LRR7-LRR8 |
Application | FACS intracellular, ImmunoFluorescence, Immunoprecipitation, Western Blot. Usage recommendation: *This monoclonal antibody may be used between 5-20 μg/ml. *Optimal dilution should be determined by each laboratory for each application. *Coupled antibody: to maintain RT before using. |
Background | The Toll-like receptor (TLR) family are considered as key for sensing microbial infections and triggering inflammatory and innate responses. 3 novel mAbs were generated against TLR3 that support the emergence of an alternative model for TLR3 biology: TLR3 full-length (TLR3FL, 130KDa) corresponds to the TLR3 present in ER, which in resting cells is steadily converted within the Golgi into fully glycosylated TLR3 (TLR3FL+, 135KDa) and then rapidly cleaved by cathepsins in the endosome/lysosome into 2 long-lived associated fragments (72 KDa and 60KDa). (Toscano F et al, J. Immunol, 2013, 190: 764–773). |
Concentration | 0.5 mg/ml |
Product Citations |
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Storage | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing. |
Format |
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Specificity |
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Accessory Products
Proteins and/or Positive Controls
Proteins for CD283 / TLR3 (3 products)
Catalog No. | Species | Pres. | Purity | Source | |||
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TP723450 |
CD283 / TLR3 |
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Human |
> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
25 µg /
$230.00
|
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OriGene Technologies, Inc. | |||||||
AR31102PU-N |
CD283 / TLR3 |
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Human | Purified | > 95 % pure by SDS-PAGE and HPLC analyses | HEK293 cells | |||
OriGene Technologies GmbH | |||||||
AR31102PU-S |
CD283 / TLR3 |
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Human | Purified | > 95 % pure by SDS-PAGE and HPLC analyses | HEK293 cells | |||
OriGene Technologies GmbH |
Positive controls for CD283 / TLR3 (1 products)
Catalog No. | Species | Pres. | Purity | Source | |||
---|---|---|---|---|---|---|---|
LY418801 |
TLR3 overexpression lysate |
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OriGene Technologies, Inc. |
Recommended Secondary Antibodies for CD283 / TLR3 (11 products)
Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
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R1253AP |
Mouse IgG (H+L chain) antibody |
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Rabbit | AP | C, E, WB | ||||
OriGene Technologies GmbH | |||||||
R1253B |
Mouse IgG (H+L chain) antibody |
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Rabbit | Biotin | C, E, WB | ||||
OriGene Technologies GmbH | |||||||
R1253F |
Mouse IgG (H+L chain) antibody |
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Rabbit | FITC | E, ICC/IF | ||||
OriGene Technologies GmbH | |||||||
R1253HRP |
Mouse IgG (H+L chain) antibody |
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Rabbit | HRP | C, E, WB | ||||
OriGene Technologies GmbH | |||||||
R1253TR |
Mouse IgG (H+L chain) antibody |
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Rabbit | Texas Red | ICC/IF | ||||
OriGene Technologies GmbH | |||||||
R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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Rabbit | PE | F | ||||
OriGene Technologies GmbH | |||||||
R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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Goat | PE | |||||
OriGene Technologies GmbH | |||||||
R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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Donkey | PE | |||||
OriGene Technologies GmbH | |||||||
R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
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Goat | Cy2 | |||||
OriGene Technologies GmbH | |||||||
R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
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Goat | Cy3 | |||||
OriGene Technologies GmbH | |||||||
R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
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Goat | Cy5 | |||||
OriGene Technologies GmbH |