AM06644SU-N B-cell linker protein / BLNK antibody

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0.1 ml / $360.00
Delivery Time: 3-5 working days*
(*) valid for US customers only

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Mouse anti Human, Mouse B-cell linker protein / BLNK 5G9

AM06644SU-N

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Product Description for B-cell linker protein / BLNK

Mouse anti Human, Mouse B-cell linker protein / BLNK 5G9.
Presentation: Ascites
Product is tested for Flow Cytometry, Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for B-cell linker protein / BLNK

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, BASH, Cytoplasmic adapter protein, SLP-65, SLP65, Src homology 2 domain-containing leukocyte protein of 65 kDa
Presentation Ascites
Reactivity Hu, Ms
Applications E, F, ICC/IF, P, WB
Clonality Monoclonal
Clone 5G9
Host Mouse
Isotype IgG1
Molecular weight 68 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8WV28
Immunogen:
Purified recombinant fragment of human BLNK expressed in E. Coli.
GeneID:
29760
Application Western Blot: 1/500 - 1/2000.
Immunohistochemistry on paraffin sections: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: 1/10000.
Background This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
General Readings
  1. J Biol Chem. 2009 Apr 10;284(15):9804-13.
  2. Cancer Sci. 2008 Dec;99(12):2444-54.
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
State:
Ascitic fluid containing 0.03% sodium azide.
Ascites
Specificity
Specificity:
This antibody reacts to BLNK.
Species:
Human and Mouse.
Gene ID 29760
FocusOn and Reviews
FocusOns:

Accessory Products

Proteins and/or Positive Controls

Proteins for B-cell linker protein / BLNK (2 products)

Catalog No. Species Pres. Purity   Source  

B-cell linker protein / BLNK (1-456, His-tag)

B-cell linker protein / BLNK Human Purified > 90 % E. coli
0.5 mg / $790.00
  Acris Antibodies GmbH

B-cell linker protein / BLNK (1-456, His-tag)

B-cell linker protein / BLNK Human Purified > 90 % E. coli
0.1 mg / $340.00
  Acris Antibodies GmbH

Positive controls for B-cell linker protein / BLNK (2 products)

Catalog No. Species Pres. Purity   Source  

BLNK overexpression lysate

BLNK overexpression lysate
0.1 mg / $295.00
  OriGene Technologies, Inc.

BLNK overexpression lysate

BLNK overexpression lysate
0.1 mg / $295.00
  OriGene Technologies, Inc.
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