TA336527 ALOX5 / LOG5 antibody

Rabbit Polyclonal 5-Lipoxygenase Antibody

See related secondary antibodies

Search for all "ALOX5 / LOG5"

0.1 ml / $395.00
Delivery Time: 5-7 working days*
(*) valid for US customers only

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Rabbit anti Human, Mouse ALOX5 / LOG5

TA336527

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  • TA336527

Product Description for ALOX5 / LOG5

Rabbit anti Human, Mouse ALOX5 / LOG5.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for ALOX5 / LOG5

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms 5-LO, 5-lipoxygenase, Arachidonate 5-lipoxygenase
Presentation Purified
Reactivity Hu, Ms
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P09917
Immunogen:
A synthetic peptide made to a region within residues 100-200 of human 5-Lipoxygenase. [Swiss-Prot# P09917].
GeneID:
240
Application WB: 1:500-1:1000
IF: 1:500 - 1:2000
Background 5-lipoxygese (5LO) is a pro-inflammatory enzyme widely expressed in CNS where its level increases in an age-dependent manner and its activity is regulated by the presence/availability of FLAP (5LO activating protein) that form a functiol complex with 5LO to catalyze arachidonic acid oxidation to produce lipid molecules with complex sigling properties such as leukotrienes. Reaction catalyzed by 5LO is considered as first step in the leukotriene biosynthesis and it is highly critical to inflammatory processes. Moreover, knockout of 5LO as well as FLAP has been shown to result in anxiety-like behavior in mice and 5LO is emerging as a new active player in Alzheimer's disease (AD) pathogenesis. 5LO levels are significantly increased in AD postmortem brain tissues and its genetic absence or pharmacological blockade both result in a significant reduction in the abeta levels as well as deposition in a transgenic mouse model of AD-like amyloidosis (i.e., Tg2576) mice.
Format
Purification:
Immunogen affinity purified
Buffer System:
PBS, 30% glycerol, 0.09% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for ALOX5 / LOG5 (1 products)

Catalog No. Species Pres. Purity   Source  

ALOX5 / LOG5

ALOX5 / LOG5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.

Positive controls for ALOX5 / LOG5 (1 products)

Catalog No. Species Pres. Purity   Source  

ALOX5 overexpression lysate

ALOX5 overexpression lysate
0.1 mg / $495.00
  OriGene Technologies, Inc.
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