AP06493PU-N ALOX5 / LOG5 antibody

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0.1 mg / $370.00
Delivery Time: 10 working days*
(*) valid for US customers only

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Rabbit anti Human, Mouse, Rat ALOX5 / LOG5

AP06493PU-N

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  • AP06493PU-N

Product Description for ALOX5 / LOG5

Rabbit anti Human, Mouse, Rat ALOX5 / LOG5.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for ALOX5 / LOG5

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms 5-LO, 5-lipoxygenase, Arachidonate 5-lipoxygenase
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~78 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P09917
Immunogen:
Synthetic peptide, corresponding to amino acids 231-280 of Human ALOX5.
GeneID:
240
Application Western blot: 1/500-1/1000.
Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Background 5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes, lipid metabolites that induce contractions of airway smooth muscle and increase vascular permeability during anaphylaxis. The cellular localization of 5-LO varies between cell types. In activated blood polymorphonuclear leukocytes 5-LO undergoes calcium dependent translocation from the cytosol to the nuclear envelope. In alveolar macrophages, the majority of 5-LO is localized in the nucleus and, upon activation of these cells, intranuclear 5-LO binds to the nuclear membrane. This intracellular shuttling of 5-LO is dependent on the associationwith various signaling molecules, phosphorylation and the presence of a distinct nuclear localization signal, which is encoded at the amino terminus of 5-LO.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen.
Buffer System:
Phosphate buffered saline (PBS), pH~7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of ALOX5 protein.
(region surrounding Glu267)
Gene ID 240

Accessory Products

Proteins and/or Positive Controls

Proteins for ALOX5 / LOG5 (1 products)

Catalog No. Species Pres. Purity   Source  

ALOX5 / LOG5

ALOX5 / LOG5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / $748.00
  OriGene Technologies, Inc.

Positive controls for ALOX5 / LOG5 (1 products)

Catalog No. Species Pres. Purity   Source  

ALOX5 overexpression lysate

ALOX5 overexpression lysate
0.1 mg / $495.00
  OriGene Technologies, Inc.
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